Codeine: Dosage of codeine Really should not be Amplified if cough fails to respond; an unresponsive cough needs to be reevaluated in five times or faster for possible underlying pathology, for instance international overall body or reduce respiratory tract sickness.
The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric clients a lot less than six several years of age, mainly because The mix may well cause lethal respiratory depression With this age population. It is crucial that promethazine hydrochloride and codeine phosphate syrup is calculated with an precise measuring unit (see PRECAUTIONS-Data for People).
Codeine: In clients obtaining MAO inhibitors, an initial compact exam dose is recommended to permit observation of any excessive narcotic effects or MAOI interaction.
fentanyl intranasal and codeine both equally increase sedation. Keep away from or Use Alternate Drug. Limit use to people for whom substitute procedure alternatives are inadequate
desipramine decreases effects of codeine by impacting hepatic enzyme CYP2D6 metabolism. Use Warning/Observe. Helps prevent conversion of codeine to its Lively metabolite morphine.
Promethazine/codeine may additionally be employed for other problems as determined by your Health care company.
The presence of other healthcare challenges could have an impact on the use of this drugs. Ensure that you tell your health care provider When you've got some other health-related challenges, Specifically:
Compound use ailment or Are living with somebody who misuses Alcoholic beverages, Avenue medications, or prescription medicines
When less widespread, quite possibly the most significant side effects of promethazine/codeine are described underneath, along with how to proceed if they transpire.
Community wellbeing strategies started addressing the hazards of misuse, emphasizing the hazards linked with opioid components. This elevated consciousness finally triggered stricter polices surrounding its prescription and distribution.
—There’s a reason regarding why Actavis Promethazine Codeine is among the most prescribed medication in the united states. It works. Actavis Promethazine Codeine is FDA permitted and clinically shown codeine promethazine actavis To ease your cough because of a dry or irritating throat, which allows you slumber greater by suppressing your cough.
diazepam buccal and codeine both enhance sedation. Stay away from or Use Alternate Drug. Restrict use to people for whom different therapy choices are inadequate
The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric sufferers under 6 decades of age. Concomitant administration of promethazine items with other respiratory depressants has an Affiliation with respiratory despair, and often death, in pediatric patients.
Epinephrine - As a result of probable for promethazine to reverse epinephrine’s vasopressor impact, epinephrine shouldn't be made use of to treat hypotension linked with promethazine overdose.